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This was unexpected because in an in vitro study, 11 the sensitivity and maximal contraction observed in response to phenylephrine were significantly reduced in aortic rings that were chronically exposed to phenylephrine compared with control aortic rings that had not been exposed to phenylephrine
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Therefore, cervical protection that might come with taking clomiphene citrate may not outweigh the possible increased chance of developing ovarian cancer
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